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Inhibition of CaMKK β and CaMK IV is detrimental in cerebral ischemia

BACKGROUND AND PURPOSE: Elevation of intracellular calcium was traditionally thought to be detrimental in stroke pathology. However, clinical trials testing treatments which block calcium signaling have failed to improve outcomes in ischemic stroke. Emerging data suggest that calcium may also trigge...

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Autores principales: McCullough, Louise D., Tarabishy, Sami, Benashski, Sharon, Xu, Yan, Ribar, Thomas, Means, Anthony, Li, Jun
Formato: Artigo
Lenguaje:Inglês
Publicado: 2013
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3845442/
https://ncbi.nlm.nih.gov/pubmed/23868268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/STROKEAHA.113.001030
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