Associations Between KCNJ6 (GIRK2) Gene Polymorphisms and Pain-Related Phenotypes

Variations in the KCNJ6 gene appear to influence both acute and chronic pain phenotypes. G-protein coupled inwardly rectifying potassium (GIRK) channels are effectors determining degree of analgesia experienced upon opioid receptor activation by endogenous and exogenous opioids. The impact of GIRK-r...

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Detalhes bibliográficos
Main Authors: Bruehl, Stephen, Denton, Jerod S., Lonergan, Daniel, Koran, Mary Ellen, Chont, Melissa, Sobey, Christopher, Fernando, Shanik, Bush, William S., Mishra, Puneet, Thornton-Wells, Tricia A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3845348/
https://ncbi.nlm.nih.gov/pubmed/23994450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pain.2013.08.026
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