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Genetic Interactions Found Between Calcium Channel Genes Modulate Amyloid Load Measured by Positron Emission Tomography

Late-onset Alzheimer’s disease (LOAD) is known to have a complex, oligogenic etiology, with considerable genetic heterogeneity. We investigated the influence of genetic interactions between genes in the Alzheimer’s disease (AD) pathway on amyloid-beta (Aβ) deposition as measured by PiB or AV-45 liga...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Koran, Mary Ellen I., Hohman, Timothy J., Thornton-Wells, Tricia A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4045094/
https://ncbi.nlm.nih.gov/pubmed/24026422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00439-013-1354-8
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