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Stearoyl CoA desaturase is required to produce active, lipid-modified Wnt proteins
Wnt proteins contain an unusual lipid modification, palmitoleic acid. Production of an active Wnt signal requires the acyltransferase Porcupine and depends on attachment of palmitoleic acid to Wnt. The source of this monounsaturated fatty acid has not been identified, and it is not known how Porcupi...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3845236/ https://ncbi.nlm.nih.gov/pubmed/24055053 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2013.08.027 |
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