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TREM2 governs Kupffer cell activation and explains belr1 genetic resistance to malaria liver stage infection

Plasmodium liver stage infection is a target of interest for the treatment of and vaccination against malaria. Here we used forward genetics to search for mechanisms underlying natural host resistance to infection and identified triggering receptor expressed on myeloid cells 2 (TREM2) and MHC class...

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Main Authors: Gonçalves, Lígia Antunes, Rodrigues-Duarte, Lurdes, Rodo, Joana, Vieira de Moraes, Luciana, Marques, Isabel, Penha-Gonçalves, Carlos
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2013
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3845107/
https://ncbi.nlm.nih.gov/pubmed/24218563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1306873110
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