Inactivation of the androgen receptor in bone-forming cells leads to trabecular bone loss in adult female mice

Removal of the androgen receptor (AR) from bone-forming cells has been shown to reduce trabecular bone volume in male mice. In female mice, the role of AR in the regulation of bone homeostasis has been poorly understood. We generated a mouse strain in which the AR is completely inactivated only in m...

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Main Authors: Määttä, Jorma A, Büki, Kalman G, Ivaska, Kaisa K, Nieminen-Pihala, Vappu, Elo, Teresa D, Kähkönen, Tiina, Poutanen, Matti, Härkönen, Pirkko, Väänänen, Kalervo
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2013
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3844973/
https://ncbi.nlm.nih.gov/pubmed/24422138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bonekey.2013.174
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