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Regulation of the transcriptome by ER stress: non-canonical mechanisms and physiological consequences
The mammalian unfolded protein response (UPR) is propagated by three ER-resident transmembrane proteins, each of which initiates a signaling cascade that ultimately culminates in production of a transcriptional activator. The UPR was originally characterized as a pathway for upregulating ER chaperon...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Frontiers Media S.A.
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3844873/ https://ncbi.nlm.nih.gov/pubmed/24348511 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2013.00256 |
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