Folate Deficiency Induces Neurodegeneration and Brain Dysfunction in Mice Lacking Uracil DNA Glycosylase

Folate deficiency and resultant increased homocysteine levels have been linked experimentally and epidemiologically with neurodegenerative conditions like stroke and dementia. Moreover, folate deficiency has been implicated in the pathogenesis of psychiatric disorders, most notably depression. We hy...

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Autors principals: Kronenberg, Golo, Harms, Christoph, Sobol, Robert W., Cardozo-Pelaez, Fernando, Linhart, Heinz, Winter, Benjamin, Balkaya, Mustafa, Gertz, Karen, Gay, Shanna B., Cox, David, Eckart, Sarah, Ahmadi, Michael, Juckel, Georg, Kempermann, Gerd, Hellweg, Rainer, Sohr, Reinhard, Hörtnagl, Heide, Wilson, Samuel H., Jaenisch, Rudolf, Endres, Matthias
Format: Artigo
Idioma:Inglês
Publicat: Society for Neuroscience 2008
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Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3844834/
https://ncbi.nlm.nih.gov/pubmed/18614692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0940-08.2008
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