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Ablation of Kv3.1 and Kv3.3 Potassium Channels Disrupts Thalamocortical Oscillations In Vitro and In Vivo

The genes Kcnc1 and Kcnc3 encode the subunits for the fast-activating/fast-deactivating, voltage-gated potassium channels Kv3.1 and Kv3.3, which are expressed in several brain regions known to be involved in the regulation of the sleep–wake cycle. When these genes are genetically eliminated, Kv3.1/K...

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Bibliographic Details
Main Authors: Espinosa, Felipe, Torres-Vega, Miguel A., Marks, Gerald A., Joho, Rolf H.
Format: Artigo
Language:Inglês
Published: Society for Neuroscience 2008
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3844809/
https://ncbi.nlm.nih.gov/pubmed/18495891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0747-08.2008
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