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Conical Electron Tomography of a Chemical Synapse: Polyhedral Cages Dock Vesicles to the Active Zone

In this study, we tested the hypothesis that the structure of the active zone of chemical synapses has remained uncertain because of limitations of conventional electron microscopy. To resolve these limitations, we reconstructed chemical synapses of rat neocortex, the archetypical “average” synapse,...

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Main Authors: Zampighi, Guido A., Fain, Nick, Zampighi, Lorenzo M., Cantele, Francesca, Lanzavecchia, Salvatore, Wright, Ernest M.
格式: Artigo
語言:Inglês
出版: Society for Neuroscience 2008
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3844767/
https://ncbi.nlm.nih.gov/pubmed/18417694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4639-07.2008
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