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Conical Electron Tomography of a Chemical Synapse: Vesicles Docked to the Active Zone are Hemi-Fused

We have used thin sectioning and conical electron tomography to determine the three-dimensional structure of synaptic vesicles that were associated (docked) at release sites of the presynaptic membrane, called active-zones. Vesicles docked at the active zone occupied a strategic location: they forme...

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Bibliografiske detaljer
Main Authors: Zampighi, G. A., Zampighi, L. M., Fain, N., Lanzavecchia, S., Simon, S. A., Wright, E. M.
Format: Artigo
Sprog:Inglês
Udgivet: Biophysical Society 2006
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1578491/
https://ncbi.nlm.nih.gov/pubmed/16877508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.106.084814
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