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Naturally Occurring Structural Isomers in Serum IgA1 O-Glycosylation

IgA is the most abundantly produced antibody and plays an important role in the mucosal immune system. Human IgA is represented by two isotypes, IgA1 and IgA2. The major structural difference between these two subclasses is the presence of nine potential sites of O-glycosylation in the hinge region...

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Detalhes bibliográficos
Main Authors: Takahashi, Kazuo, Smith, Archer D., Poulsen, Knud, Kilian, Mogens, Julian, Bruce A., Mestecky, Jiri, Novak, Jan, Renfrow, Matthew B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3844682/
https://ncbi.nlm.nih.gov/pubmed/22067045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/pr200608q
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