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Peripheral CD4(+) T-cell tolerance is induced in vivo by rare antigen-bearing B cells in follicular, marginal zone, and B-1 subsets

B cells are efficient APCs when they internalize antigen via BCR-mediated uptake. Adoptively transferred antigen-presenting B cells can induce T-cell tolerance to foreign and self antigens; however, it is unknown whether endogenous B cells presenting self-peptides interact with naïve T cells and con...

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Bibliografiska uppgifter
Huvudupphovsmän: Murray, Susan E., Gardner Toren, Katelynne, Parker, David C.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2013
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3844680/
https://ncbi.nlm.nih.gov/pubmed/23532986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201242784
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