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The Effect of Transient Increases in Kynurenic Acid and Quinolinic Acid Levels Early in Life on Behavior in Adulthood: Implications for Schizophrenia

Kynurenic acid is a tryptophan metabolite that is synthesized and released in the brain by astrocytes and acts as an antagonist of nicotinic acetylcholine receptors and N-methyl-D-aspartate glutamate receptors, both of which are critically involved in cognition as well as neural plasticity and brain...

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Bibliographic Details
Main Authors: Iaccarino, Hannah F., Suckow, Raymond F., Xie, Shan, Bucci, David J.
Format: Artigo
Language:Inglês
Published: 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3844520/
https://ncbi.nlm.nih.gov/pubmed/24091034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.schres.2013.09.004
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