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Post-translational regulation enables robust p53 regulation

BACKGROUND: The tumor suppressor protein p53 plays important roles in DNA damage repair, cell cycle arrest and apoptosis. Due to its critical functions, the level of p53 is tightly regulated by a negative feedback mechanism to increase its tolerance towards fluctuations and disturbances. Interesting...

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Detalhes bibliográficos
Main Authors: Shin, Yong-Jun, Chen, Kai-Yuan, Sayed, Ali H, Hencey, Brandon, Shen, Xiling
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3844394/
https://ncbi.nlm.nih.gov/pubmed/23992617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1752-0509-7-83
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