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Post-translational regulation enables robust p53 regulation
BACKGROUND: The tumor suppressor protein p53 plays important roles in DNA damage repair, cell cycle arrest and apoptosis. Due to its critical functions, the level of p53 is tightly regulated by a negative feedback mechanism to increase its tolerance towards fluctuations and disturbances. Interesting...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
BioMed Central
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3844394/ https://ncbi.nlm.nih.gov/pubmed/23992617 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1752-0509-7-83 |
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