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Growth Arrest on Inhibition of Nonsense-Mediated Decay Is Mediated by Noncoding RNA GAS5

Nonsense-mediated decay is a key RNA surveillance mechanism responsible for the rapid degradation of mRNAs containing premature termination codons and hence prevents the synthesis of truncated proteins. More recently, it has been shown that nonsense-mediated decay also has broader significance in co...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Mourtada-Maarabouni, Mirna, Williams, Gwyn T.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Hindawi Publishing Corporation 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3844204/
https://ncbi.nlm.nih.gov/pubmed/24319682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/358015
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