Cytoplasmic translocation of the retinoblastoma protein disrupts sarcomeric organization

Skeletal muscle degeneration is a complication arising from a variety of chronic diseases including advanced cancer. Pro-inflammatory cytokine TNF-α plays a pivotal role in mediating cancer-related skeletal muscle degeneration. Here, we show a novel function for retinoblastoma protein (Rb), where Rb...

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Bibliographic Details
Main Authors: Araki, Keigo, Kawauchi, Keiko, Hirata, Hiroaki, Yamamoto, Mie, Taya, Yoichi
Format: Artigo
Language:Inglês
Published: eLife Sciences Publications, Ltd 2013
Subjects:
Cell Biology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3843810/
https://ncbi.nlm.nih.gov/pubmed/24302570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.01228
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