Smooth Muscle LDL Receptor-Related Protein-1 Deletion Induces Aortic Insufficiency and Promotes Vascular Cardiomyopathy in Mice

Valvular disease is common in patients with Marfan syndrome and can lead to cardiomyopathy. However, some patients develop cardiomyopathy in the absence of hemodynamically significant valve dysfunction, suggesting alternative mechanisms of disease progression. Disruption of LDL receptor-related prot...

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Detalhes bibliográficos
Main Authors: Basford, Joshua E., Koch, Sheryl, Anjak, Ahmad, Singh, Vivek P., Krause, Eric G., Robbins, Nathan, Weintraub, Neal L., Hui, David Y., Rubinstein, Jack
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3843717/
https://ncbi.nlm.nih.gov/pubmed/24312398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0082026
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