Phosphatidylinositol 3-kinase (PI3K) inhibitors as cancer therapeutics

Phosphatidylinositol 3-kinases (PI3Ks) are lipid kinases that regulate diverse cellular processes including proliferation, adhesion, survival, and motility. Dysregulated PI3K pathway signaling occurs in one-third of human tumors. Aberrantly activated PI3K signaling also confers sensitivity and resis...

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Bibliographic Details
Main Authors: Akinleye, Akintunde, Avvaru, Parthu, Furqan, Muhammad, Song, Yongping, Liu, Delong
Format: Artigo
Language:Inglês
Published: BioMed Central 2013
Subjects:
Review
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3843585/
https://ncbi.nlm.nih.gov/pubmed/24261963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-8722-6-88
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