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Phosphatidylinositol 3-kinase (PI3K) inhibitors as cancer therapeutics
Phosphatidylinositol 3-kinases (PI3Ks) are lipid kinases that regulate diverse cellular processes including proliferation, adhesion, survival, and motility. Dysregulated PI3K pathway signaling occurs in one-third of human tumors. Aberrantly activated PI3K signaling also confers sensitivity and resis...
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| Главные авторы: | , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
BioMed Central
2013
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3843585/ https://ncbi.nlm.nih.gov/pubmed/24261963 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-8722-6-88 |
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