Mild chronic cerebral hypoperfusion induces neurovascular dysfunction, triggering peripheral beta-amyloid brain entry and aggregation

BACKGROUND: The Blood–brain barrier (BBB) controls brain supply with oxygen and nutrients, and protects the brain from toxic metabolites, such as beta-amyloid (Aβ) peptides. The neurovascular unit (NVU) couples vascular and neuronal functions by controlling BBB parameters based on brain needs. As su...

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Detaylı Bibliyografya
Asıl Yazarlar: ElAli, Ayman, Thériault, Peter, Préfontaine, Paul, Rivest, Serge
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2013
Konular:
Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3843528/
https://ncbi.nlm.nih.gov/pubmed/24252187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2051-5960-1-75
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