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A domain in the N-terminal extension of class IIb eukaryotic aminoacyl-tRNA synthetases is important for tRNA binding

Cytoplasmic aspartyl-tRNA synthetase (AspRS) from Saccharomyces cerevisiae is a homodimer of 64 kDa subunits. Previous studies have emphasized the high sensitivity of the N-terminal region to proteolytic cleavage, leading to truncated species that have lost the first 20–70 residues but that retain e...

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Hlavní autoři: Frugier, Magali, Moulinier, Luc, Giegé, Richard
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2000
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC384352/
https://ncbi.nlm.nih.gov/pubmed/10811628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/19.10.2371
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