Efficient aminoacylation of resected RNA helices by class II aspartyl-tRNA synthetase dependent on a single nucleotide.

We show here that small RNA helices which recapitulate part or all of the acceptor stem of yeast aspartate tRNA are efficiently aminoacylated by cognate class II aspartyl-tRNA synthetase. Aminoacylation is strongly dependent on the presence of the single-stranded G73 'discriminator' identi...

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Veröffentlicht in:EMBO J
Hauptverfasser: Frugier, M, Florentz, C, Giegé, R
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 1994
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC395077/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8187774/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1994.tb06499.x
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