Critical role played by thyroid hormone in induction of neoplastic transformation by chemical carcinogens in tissue culture.

Incubation of primary cultures of hamster embryo cells (HEC) or mouse fibroblasts (C3H/10T1/2 cells) in media depleted of thyroid hormones does not alter cell growth or survival but renders the cells resistant to neoplastic transformation by benzo[a]pyrene (B[a]P) or N-methyl-N'-nitro-N-nitroso...

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Main Authors: Borek, C, Guernsey, D L, Ong, A, Edelman, I S
Format: Artigo
Sprog:Inglês
Udgivet: 1983
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC384336/
https://ncbi.nlm.nih.gov/pubmed/6310591
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