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Critical role played by thyroid hormone in induction of neoplastic transformation by chemical carcinogens in tissue culture.
Incubation of primary cultures of hamster embryo cells (HEC) or mouse fibroblasts (C3H/10T1/2 cells) in media depleted of thyroid hormones does not alter cell growth or survival but renders the cells resistant to neoplastic transformation by benzo[a]pyrene (B[a]P) or N-methyl-N'-nitro-N-nitroso...
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| Udgivet i: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
1983
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC384336/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6310591/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.80.18.5749 |
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