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Radical Synthesis Opens Access to Organometallic Aryl-Cobaltcorrins - 4-Ethylphenyl-cobalamin, a Potential ‘Antivitamin-B(12)’

[Image: see text] 4-Ethylphenyl-cobalamin, a novel organometallic aryl-cobalamin, was synthesized in a radical reaction. This organometallic B(12) features a strong (Co-C)-bond, and represents a ‘locked’ form of vitamin B(12). This B(12)-antimetabolite may be used in animal studies to induce ‘functi...

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Detalhes bibliográficos
Main Authors: Ruetz, Markus, Gherasim, Carmen, Gruber, Karl, Fedosov, Sergey, Banerjee, Ruma, Kräutler, Bernhard
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3843227/
https://ncbi.nlm.nih.gov/pubmed/23404623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201209651
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