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PEGylated G-CSF (BBT-015), GM-CSF (BBT-007), and IL-11 (BBT-059) analogs enhance survival and hematopoietic cell recovery in a mouse model of the Hematopoietic Syndrome of the Acute Radiation Syndrome

Hematopoietic growth factors (HGF) are recommended therapy for high dose radiation exposure, but unfavorable administration schedules requiring early and repeat dosing limit the logistical ease with which they can be used. In this report, utilizing our previously described murine model of H-ARS, sur...

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Bibliographic Details
Main Authors: Plett, P. Artur, Chua, Hui Lin, Sampson, Carol H., Katz, Barry P., Fam, Christine M., Anderson, Lana J., Cox, George, Orschell, Christie M.
Format: Artigo
Language:Inglês
Published: 2014
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3843149/
https://ncbi.nlm.nih.gov/pubmed/24276546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/HP.0b013e3182a4dd4e
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