Establishing a murine model of the Hematopoietic Syndrome of the Acute Radiation Syndrome

We have developed a murine model of the Hematopoietic Syndrome of the Acute Radiation Syndrome (H-ARS) for efficacy testing of medical countermeasures (MCM) against radiation according to the FDA Animal Rule. Ten to 12 week old male and female C57BL/6 mice were exposed to the LD50/30-LD70/30 dose of...

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Bibliographic Details
Main Authors: Plett, P. Artur, Sampson, Carol H., Chua, Hui Lin, Joshi, Mandar, Booth, Catherine, Gough, Alec, Johnson, Cynthia S., Katz, Barry P., Farese, Ann M., Parker, Jeffrey, MacVittie, Thomas J., Orschell, Christie M.
Format: Artigo
Language:Inglês
Published: 2012
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3743168/
https://ncbi.nlm.nih.gov/pubmed/22929467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/HP.0b013e3182667309
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