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Chitosan oligosaccharides block LPS-induced O-GlcNAcylation of NF-κB and endothelial inflammatory response

It is known that chitosan oligosaccharides (COS) suppress LPS-induced vascular endothelial inflammatory response by mechanism involving NF-κB blockade. It remains unknown how COS inhibit NF-κB. We provided evidence both in cultured endothelial cells and mouse model supporting a new mechanism. Regard...

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Detalhes bibliográficos
Main Authors: Li, Yu, Liu, Hongtao, Xu, Qing-Song, Du, Yu-Guang, Xu, Jian
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3843148/
https://ncbi.nlm.nih.gov/pubmed/24274545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.carbpol.2013.08.082
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