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NFκB activation is associated with its O-GlcNAcylation state under hyperglycemic conditions
The transcription factor NFκB is activated by phosphorylation and acetylation and plays important roles in inflammatory and immune responses in the cell. Additionally, posttranslational modification of the NFκB p65 subunit by O-linked N-acetylglucosamine (O-GlcNAc) has been reported, but the modific...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2582288/ https://ncbi.nlm.nih.gov/pubmed/18988733 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0806198105 |
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