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NFκB activation is associated with its O-GlcNAcylation state under hyperglycemic conditions

The transcription factor NFκB is activated by phosphorylation and acetylation and plays important roles in inflammatory and immune responses in the cell. Additionally, posttranslational modification of the NFκB p65 subunit by O-linked N-acetylglucosamine (O-GlcNAc) has been reported, but the modific...

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Bibliografiske detaljer
Main Authors: Yang, Won Ho, Park, Sang Yoon, Nam, Hyung Wook, Kim, Do Hyun, Kang, Jeong Gu, Kang, Eun Seok, Kim, Yu Sam, Lee, Hyun Chul, Kim, Kwan Soo, Cho, Jin Won
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2582288/
https://ncbi.nlm.nih.gov/pubmed/18988733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0806198105
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