Aralia elata inhibits neurodegeneration by downregulating O-GlcNAcylation of NF-κB in diabetic mice

AIM: To investigate the role of O-GlcNAcylation of nuclear factor-kappa B (NF-κB) in retinal ganglion cell (RGC) death and analysedthe effect of Aralia elata (AE) on neurodegeneration in diabetic mice. METHODS: C57BL/6mice with streptozotocin-induced diabetes were fed daily with AE extract or contro...

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Bibliografski detalji
Izdano u:Int J Ophthalmol
Glavni autori: Kim, Seong-Jae, Kim, Min-Jun, Choi, Mee-Young, Kim, Yoon-Sook, Yoo, Ji-Myong, Hong, Eun-Kyung, Ju, Sunmi, Choi, Wan-Sung
Format: Artigo
Jezik:Inglês
Izdano: International Journal of Ophthalmology Press 2017
Teme:
Basic Research
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5554836/
https://ncbi.nlm.nih.gov/pubmed/28861343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18240/ijo.2017.08.03
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