A functional siRNA screen identifies genes modulating angiotensin II-mediated EGFR transactivation

The angiotensin type 1 receptor (AT(1)R) transactivates the epidermal growth factor receptor (EGFR) to mediate cellular growth, however, the molecular mechanisms involved have not yet been resolved. To address this, we performed a functional siRNA screen of the human kinome in human mammary epitheli...

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Detalhes bibliográficos
Main Authors: George, Amee J., Purdue, Brooke W., Gould, Cathryn M., Thomas, Daniel W., Handoko, Yanny, Qian, Hongwei, Quaife-Ryan, Gregory A., Morgan, Kylie A., Simpson, Kaylene J., Thomas, Walter G., Hannan, Ross D.
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3843137/
https://ncbi.nlm.nih.gov/pubmed/24046455
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.128280
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