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Total Synthesis and Biological Evaluation of an Antifungal Tricyclic o-Hydroxy-p-Quinone Methide Diterpenoid
A convergent route has been developed to synthesize an antifungal tricyclic o-hydroxy-p-quinone methide diterpenoid and analogs. The Li/naphthalene mediated reductive alkylation was employed for coupling β-cyclocitral and the corresponding benzyl chloride while the BBr(3)–mediated one-pot bis-demeth...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3843042/ https://ncbi.nlm.nih.gov/pubmed/23957833 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jo4013964 |
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