Disruption of Orbitofronto-Striatal Functional Connectivity Underlies Maladaptive Persistent Behaviors in Alcohol-Dependent Patients

OBJECTIVE: Alcohol dependence is characterized by persistent alcohol-seeking despite negative consequences. Previous studies suggest that maladaptive persistent behaviors reflect alcohol-induced brain changes that cause alterations in the cortico-striatal-limbic circuit. METHODS: Twenty one alcohol...

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Autori principali: Lee, Seojung, Lee, Eun, Ku, Jeonghun, Yoon, Kang-Jun, Namkoong, Kee, Jung, Young-Chul
Natura: Artigo
Lingua:Inglês
Pubblicazione: Korean Neuropsychiatric Association 2013
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3843019/
https://ncbi.nlm.nih.gov/pubmed/24302950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4306/pi.2013.10.3.266
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