Concerted Suppression of STAT3 and GSK3β Is Involved in Growth Inhibition of Non-Small Cell Lung Cancer by Xanthatin

Xanthatin, a sesquiterpene lactone purified from Xanthium strumarium L., possesses prominent anticancer activity. We found that disruption of GSK3β activity was essential for xanthatin to exert its anticancer properties in non-small cell lung cancer (NSCLC), concurrent with preferable suppression of...

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Detalhes bibliográficos
Main Authors: Tao, Li, Fan, Fangtian, Liu, Yuping, Li, Weidong, Zhang, Lei, Ruan, Junshan, Shen, Cunsi, Sheng, Xiaobo, Zhu, Zhijie, Wang, Aiyun, Chen, Wenxing, Huang, Shile, Lu, Yin
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3842975/
https://ncbi.nlm.nih.gov/pubmed/24312384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0081945
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