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NEDD4L Is Downregulated in Colorectal Cancer and Inhibits Canonical WNT Signaling
The NEDD4 family of E3 ubiquitin ligases includes nine members. Each is a modular protein, containing an N-terminal C2 domain for cell localization, two-to-four central WW domains for substrate recognition, and a C-terminal, catalytic HECT domain, which is responsible for catalyzing the ubiquitylati...
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| Hlavní autoři: | , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Public Library of Science
2013
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3842946/ https://ncbi.nlm.nih.gov/pubmed/24312311 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0081514 |
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