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Hippocampal Glutamate NMDA Receptor Loss Tracks Progression in Alzheimer’s Disease: Quantitative Autoradiography in Postmortem Human Brain

Early Alzheimer's disease (AD) is characterized by memory loss and hippocampal atrophy with relative sparing of basal ganglia. Activation of glutamate NMDA receptors in the hippocampus is an important step in memory formation. We measured the density of NMDA receptors in samples of hippocampus,...

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Detalhes bibliográficos
Main Authors: Kravitz, Efrat, Gaisler-Salomon, Inna, Biegon, Anat
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3842934/
https://ncbi.nlm.nih.gov/pubmed/24312282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0081244
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