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Hippocampal Glutamate NMDA Receptor Loss Tracks Progression in Alzheimer’s Disease: Quantitative Autoradiography in Postmortem Human Brain

Early Alzheimer's disease (AD) is characterized by memory loss and hippocampal atrophy with relative sparing of basal ganglia. Activation of glutamate NMDA receptors in the hippocampus is an important step in memory formation. We measured the density of NMDA receptors in samples of hippocampus,...

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Bibliografiske detaljer
Main Authors: Kravitz, Efrat, Gaisler-Salomon, Inna, Biegon, Anat
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3842934/
https://ncbi.nlm.nih.gov/pubmed/24312282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0081244
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