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Role of glutamate and NMDA receptors in Alzheimer’s disease

Excitatory glutamatergic neurotransmission via N-methyl-d-aspartate receptor (NMDAR) is critical for synaptic plasticity and survival of neurons. However, excessive NMDAR activity causes excitotoxicity and promotes cell death, underlying a potential mechanism of neurodegeneration occurred in Alzheim...

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Detalhes bibliográficos
Publicado no:J Alzheimers Dis
Main Authors: Wang, Rui, Reddy, P. Hemachandra
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5791143/
https://ncbi.nlm.nih.gov/pubmed/27662322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-160763
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