Fast in vitro methods to determine the speed of action and the stage-specificity of anti-malarials in Plasmodium falciparum

BACKGROUND: Recent whole cell in vitro screening campaigns identified thousands of compounds that are active against asexual blood stages of Plasmodium falciparum at submicromolar concentrations. These hits have been made available to the public, providing many novel chemical starting points for ant...

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Detalhes bibliográficos
Principais autores: Le Manach, Claire, Scheurer, Christian, Sax, Sibylle, Schleiferböck, Sarah, Cabrera, Diego Gonzalez, Younis, Yassir, Paquet, Tanya, Street, Leslie, Smith, Peter, Ding, Xavier C, Waterson, David, Witty, Michael J, Leroy, Didier, Chibale, Kelly, Wittlin, Sergio
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3842807/
https://ncbi.nlm.nih.gov/pubmed/24237770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2875-12-424
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