Deficiency of an erythrocyte membrane protein with complement regulatory activity in paroxysmal nocturnal hemoglobinuria.

Paroxysmal nocturnal hemoglobinuria (PNH) is an acquired hemolytic anemia in which the erythrocytes are abnormally sensitive to lysis by complement. A functional deficiency of membrane-associated complement regulators has been demonstrated on PNH erythrocytes. The two factor H-like proteins, the C3b...

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Publié dans:	Proc Natl Acad Sci U S A
Auteurs principaux:	Pangburn, M K, Schreiber, R D, Müller-Eberhard, H J
Format:	Artigo
Langue:	Inglês
Publié:	National Academy of Sciences 1983
Sujets:	Research Article
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC384270/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6225118/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.80.17.5430
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