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Use of a cDNA clone for the fourth component of human complement (C4) for analysis of a genetic deficiency of C4 in guinea pig.

A cDNA clone for the fourth complement component (C4), pC4AL1, has been isolated from a human adult liver cDNA library by using a synthetic oligonucleotide mixture containing all 384 possible sequences coding for residues 14-21 of the C4 gamma-chain amino acid sequence. This clone spans the entire C...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Whitehead, A S, Goldberger, G, Woods, D E, Markham, A F, Colten, H R
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 1983
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC384261/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6577433/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.80.17.5387
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