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Guinea pigs with inherited deficiencies of complement components C2 or C4 have characteristics of immune complex disease.

Guinea pigs genetically deficient in the second (C2) or fourth component of complement (C4) generally appear healthy in contrast to humans with a C2 or C4 deficiency. However, upon investigation of these genetic deficiencies in guinea pigs for signs of dysregulation in the humoral immune system and...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Böttger, E C, Hoffmann, T, Hadding, U, Bitter-Suermann, D
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 1986
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC423652/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2427541/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI112628
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