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Spinal Matrix Metalloproteinase-9 Contributes to Physical Dependence on Morphine in Mice
Preventing and reversing opioid dependence continues to be a clinical challenge and underlying mechanisms of opioid actions remain elusive. We report that matrix metalloproteinase-9 (MMP-9) in the spinal cord contributes to development of physical dependence on morphine. Chronic morphine exposure an...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Society for Neuroscience
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3842477/ https://ncbi.nlm.nih.gov/pubmed/20519536 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1358-10.2010 |
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