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Defective acidification of endosomes in Chinese hamster ovary cell mutants "cross-resistant" to toxins and viruses.

Like many physiological ligands, several viruses and toxins enter mammalian cells through receptor-mediated endocytosis. Once internalized, the nucleic acids of several viruses and the toxic subunit of diphtheria toxin gain access to the cytosol of the host cell through an acidic intracellular compa...

詳細記述

保存先:
書誌詳細
主要な著者: Merion, M, Schlesinger, P, Brooks, R M, Moehring, J M, Moehring, T J, Sly, W S
フォーマット: Artigo
言語:Inglês
出版事項: 1983
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC384246/
https://ncbi.nlm.nih.gov/pubmed/6577430
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