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Adrenergic Regulation of IgE Involves Modulation of CD23 and ADAM10 Expression on Exosomes

Soluble CD23 (sCD23) plays a role in the positive regulation of an IgE response. Engagement of the beta-2 adrenergic receptor (β(2)AR) on a B cell is known to enhance the level of both sCD23 and IgE, although the mechanism by which this occurs is not completely understood. We report herein that, in...

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Main Authors: Padro, Caroline J., Shawler, Todd M., Gormley, Matthew G., Sanders, Virginia M.
Format: Artigo
Jezik:Inglês
Izdano: 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3842235/
https://ncbi.nlm.nih.gov/pubmed/24140643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1301019
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