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The Low Affinity IgE Receptor (CD23) Is Cleaved by the Metalloproteinase ADAM10
The low affinity IgE receptor, Fc∊RII (CD23), is both a positive and negative regulator of IgE synthesis. The proteinase activity that converts the membrane-bound form of CD23 into a soluble species (sCD23) is an important regulator of the function of CD23 and may be an important therapeutic target...
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| Autores principales: | , , , , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2007
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2582392/ https://ncbi.nlm.nih.gov/pubmed/17389606 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M608414200 |
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