The Low Affinity IgE Receptor (CD23) Is Cleaved by the Metalloproteinase ADAM10

The low affinity IgE receptor, Fc∊RII (CD23), is both a positive and negative regulator of IgE synthesis. The proteinase activity that converts the membrane-bound form of CD23 into a soluble species (sCD23) is an important regulator of the function of CD23 and may be an important therapeutic target...

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Hlavní autoři: Lemieux, George A., Blumenkron, Fernando, Yeung, Nolan, Zhou, Pei, Williams, Jason, Grammer, Amrie C., Petrovich, Robert, Lipsky, Peter E., Moss, Marcia L., Werb, Zena
Médium: Artigo
Jazyk:Inglês
Vydáno: 2007
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2582392/
https://ncbi.nlm.nih.gov/pubmed/17389606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M608414200
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