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PI3 kinase directly phosphorylates Akt1/2 at Ser473/474 in the insulin signal transduction pathway
Insulin stimulated translocation of the glucose transporter GLUT4 from the cytosol to the plasma membrane in a concentration (1 nM–1 μM)-dependent manner and increased glucose uptake in 3T3-L1 adipocytes. Insulin-induced GLUT4 translocation to the cell surface was prevented by the phosphoinositide 3...
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| Auteurs principaux: | , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Bioscientifica Ltd
2014
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3842210/ https://ncbi.nlm.nih.gov/pubmed/24169049 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1530/JOE-13-0172 |
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