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Complementary Phosphorylation Sites in the Adaptor Protein SLP-76 Promote Synergistic Activation of Natural Killer Cells

The cytotoxic effects of natural killer (NK) cells and their ability to secrete cytokines require the induction of synergistic signals from co-activation receptors, such as CD314 (NKG2D) and CD244 (2B4), which bind to ligands expressed on target cells. Synergy is required to overcome inhibition of t...

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Kaydedildi:
Detaylı Bibliyografya
Asıl Yazarlar: Kim, Hun Sik, Long, Eric O.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2012
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3842037/
https://ncbi.nlm.nih.gov/pubmed/22786724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.2002754
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