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Heterochromatin establishment at pericentromeres depends on nuclear position

Mammalian development begins with fertilization of an oocyte by the sperm followed by genome-wide epigenetic reprogramming. This involves de novo establishment of chromatin domains, including the formation of pericentric heterochromatin. We dissected the spatiotemporal kinetics of the first acquisit...

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Hauptverfasser: Jachowicz, Joanna W., Santenard, Angèle, Bender, Ambre, Muller, Julius, Torres-Padilla, Maria-Elena
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cold Spring Harbor Laboratory Press 2013
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3841731/
https://ncbi.nlm.nih.gov/pubmed/24240232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.224550.113
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