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Computational Prediction of Drug Solubility in Lipid Based Formulation Excipients
PURPOSE: To investigate if drug solubility in pharmaceutical excipients used in lipid based formulations (LBFs) can be predicted from physicochemical properties. METHODS: Solubility was measured for 30 structurally diverse drug molecules in soybean oil (SBO, long-chain triglyceride; TG(LC)), Captex3...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer US
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3841656/ https://ncbi.nlm.nih.gov/pubmed/23771564 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-013-1083-7 |
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