Methylation of replicating and post-replicated mouse L-cell DNA.
We have introduced [alpha-32P]dGTP into permeabilized cells and measured the degree of methylation at CpG sites by nearest-neighbor analysis. This method reveals a lag of approximately 1 min between DNA synthesis and the modification event. When methylation is inhibited by the addition of S-adenosyl...
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| 發表在: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
National Academy of Sciences
1983
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC384158/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6576364/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.80.16.4919 |
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